Equol

Product Name: Equol
CAS No.: 531-95-3
Chemical Name: Equol
Synonyms: Equol;(S)-EQUOL;R,S-EQUOL;S,R-equol;(3S)-Equol;(-)-(S)-EQUOL;Equol USP/EP/BP;EQUOL, (+/-)-(SH);(S)-Equol,99%e.e.;4',7-ISOFLAVANDIOL
CBNumber: CB2317528
Molecular Formula: C15H14O3
Formula Weight: 242.27
MOL File: 531-95-3.mol

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Equol Property

Melting point:: 189-190°C
alpha: D -21.5°
Boiling point:: 312.25°C (rough estimate)
Density: 1.1914 (rough estimate)
refractive index: 1.5557 (estimate)
storage temp.: Inert atmosphere,2-8°C
solubility: DMSO (Soluble), Ethanol (Slightly), Methanol (Slightly)
pka: 9.94±0.40(Predicted)
form: Solid
color: White to Pale Yellow
CAS DataBase Reference: 531-95-3(CAS DataBase Reference)

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Safety

WGK Germany: 3
F: 3-10

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 10010173
Product name: (S)-Equol
Purity: ≥98%
Packaging: 1mg
Price: $21
Updated: 2024/03/01

Cayman Chemical

Product number: 10010173
Product name: (S)-Equol
Purity: ≥98%
Packaging: 5mg
Price: $89
Updated: 2024/03/01

Cayman Chemical

Product number: 10010173
Product name: (S)-Equol
Purity: ≥98%
Packaging: 10mg
Price: $157
Updated: 2024/03/01

Cayman Chemical

Product number: 10010173
Product name: (S)-Equol
Purity: ≥98%
Packaging: 25mg
Price: $341
Updated: 2024/03/01

Tocris

Product number: 6158
Product name: (S)-Equol
Purity: ≥98%(HPLC)
Packaging: 10
Price: $122
Updated: 2021/12/16

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Equol Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Solid

Uses

Receptor; binding activity

Uses

A human urinary metabolite of Daidzein. It is also a natural estrogenic metabolite from soy isoflavones

Uses

serine protease

Uses

(S)-Equol and R-Equol are metabolites of the soy isoflavones Daidzein (D103500) and Genistein. Both have significant biological actions.

Definition

ChEBI: Equol is a member of hydroxyisoflavans.

Biological Activity

equol is an isoflavan produced by intestinal bacteria in response to soy isoflavone intake in human. it shows a wide range of activities including antioxidant activity, anti-inflammation activity and anticancer activity. it is reported that equol specifically binds to 5α-dht and has a modest affinity for recombinant estrogen receptor erβ, which may be responsible for most of equol’s biological properties. [1]

in vitro

in vitro studies were conducted to measure both the binding affinity of equol for 5alpha-dihydrotestosterone (5alpha-dht) and the effects of equol treatment in human prostate cancer (lncap) cells. it was found that equol bound to 5alpha-dht with maximum and half maxim concentrations of 100 nm and 4.8 nm, respectively. in addition, equol significantly offset the increases in psa levels from lncap cells. [1]

in vivo

an in vivo study was performed to investigate effects of equol on rat prostate weight and circulating levels of sex steroid hormones. 1.0 mg/kg of equol was injected to long-evans rats fed with a low isoflavone diet for 25 days. findings from this study suggested that equol significantly decreased rat prostate weights and down-regulated serum levels of 5alpha-dht. however, this agent did not alter levels of lh, testosterone and estradiol. [1]

References

[1]lund td, blake c, bu l, hamaker an, lephart ed. iequol an isoflavonoid: potential for improved prostate health, in vitro and in vivo evidence. reprod biol endocrin. 2011; 9(4): doi: 10.1186/1477-7827-9-4.
[2]setchell dr and clerici c. equol: pharmacokinetics and biological actions. j nutr. 2010 jul; 140(7): 1363s–8s.

Equol Preparation Products And Raw materials

Raw materials

Preparation Products

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Equol Suppliers

Canada 1 China 219 Europe 2 Germany 2 India 5 Japan 1 Switzerland 1 United Kingdom 6 United States 27 Global 264

HBCChem, Inc.

Tel: +1-510-219-6317
Fax: +1-650-486-1361
Email: sales@hbcchem.com
Country: United States
ProdList: 10658
Advantage: 60

ALB Technology Limited

Tel: 702-983-3769
Fax: 702-983-3769
Email: sales@albtechnology.com
Country: United States
ProdList: 2993
Advantage: 55

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8449
Advantage: 60

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
Advantage: 60

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6393
Advantage: 58

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63711
Advantage: 58

Aladdin Scientific

Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57511
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354
Email: support@targetmol.com
Country: United States
ProdList: 19973
Advantage: 58

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View Lastest Price from Equol manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.

Product: Equol; Soybean extract 531-95-3
Price: US $0.00/KG
Min. Order: 1KG
Purity: >99% HPLC
Supply Ability: 1000KG
Release date: 2022-09-16

Hebei Kingfiner Technology Development Co.Ltd

Product: Equol 531-95-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 50000kg
Release date: 2023-09-19

Nanjing Kaitian Chemical Co., LTD

Product: Equol 531-95-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2 tons
Release date: 2022-12-06

531-95-3, EquolRelated Search:

Dihydromyrcenol Hydroxy silicone oil Triphenylphosphine Tetrahydro-4H-pyran-4-one Centchroman 2-Phenylphenol Aspartame TRIFOLIRHIZIN Rotenone MEDICARPIN morelloflavone Phenylacetone Phenoxodiol pisatin 4',7-DIMETHOXYISOFLAVANONE Dihydrodaidzein Phaseollin (-)-TEPHROSIN

(S)-3,4-DYHYDRO-3-(4-HYDROXYPHENYL)-2H-1-BENZOPYRAN-7-OL

(S)-4',7-DIHYDROXYISOFLAVANCE

R,S-EQUOL

(-)-(S)-EQUOL

S,R-equol

3-(4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol

4',7-ISOFLAVANDIOL

4',7-DIHYDROXYISOFLAVAN

7,4'-ISOFLAVANDIOL

(S)-3,4-dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol

(S)-EQUOL

(S)-3-(4-Hydroxy-phenyl)-chroman-7-ol

3-(4-Hydroxy-phenyl)-chroman-7-ol

(3S)-3-(4-hydroxyphenyl)chroman-7-ol

EQUOL, (+/-)-(SH)

EQUOL/()-4'',7-ISOFLAVANDIOL

(S)-(-)-4',7-Isoflavandiol

(3S)-3-(4-Hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol

(3S)-Equol

Equol

(3S)-3-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-ol

S -Equol [7-hydroxy-3-(49-hydroxyphenyl)-chroMan]

2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(4-hydroxyphenyl)-, (3S)-

(S)-Equol,99%e.e.

(3S)-3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol

Equol USP/EP/BP

4-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-156-THIOSEMICARBAZIDE

(S)-Equol/2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(4-hydroxyphenyl)-, (3S)-

(S)-7-phenoxy-3-(4-phenoxyphenyl)chromane

531-95-3

Food Residue Analysis

Analytical Standards

Analytical Chromatography Product Catalog

Food & Beverage Standards

Chromatography

Inhibitors

Iso-Flavones

Chiral Reagents

Heterocycles

Metabolites & Impurities

Metabolites